Direct effects of thyroid hormones on hepatic lipid metabolism
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چکیده
منابع مشابه
Effects of adrenalectomy and dexamethasone on hepatic lipid metabolism.
The influence of adrenalectomy and dexamethasone on hepatic free fatty acid metabolism was studied in isolated perfused livers from male rats. Adrenalectomy 1 week prior to perfusion did not affect uptake of oleate, output of triglyceride, or rate of ketogenesis compared to sham-operated match-fed controls. Livers from dexamethasone-treated rats (0-2 mg/kg per day for 7 days) removed less oleat...
متن کاملEffects of adrenalectomy and dexamethasone on hepatic lipid metabolism'
The influence of adrenalectomy and dexamethasone on hepatic free fatty acid metabolism was studied in isolated perfused livers from male rats. Adrenalectomy 1 week prior to perfusion did not affect uptake of oleate, output of triglyceride, or rate of ketogenesis compared to sham-operated match-fed controls. Livers from dexamethasone-treated rats (0-2 mg/kg per day for 7 days) removed less oleat...
متن کاملEffects of thyroid hormones on the heart.
Thyroid hormones have a significant impact on heart function, mediated by genomic and non-genomic effects. Consequently, thyroid hormone deficiencies, as well as excesses, are expected to result in profound changes in cardiac function regulation and cardiovascular hemodynamics. Thyroid hormones upregulate the expression of the sarcoplasmic reticulum calcium-activated ATPase and downregulate the...
متن کاملUpdate on Lipid Metabolism and Thyroid Disorders
Thyroid hormone plays an important role in the regulation of lipid metabolism. It acts predominantly through its nuclear receptors (thyroid hormone receptor α and β) to regulate the gene expression related to lipid metabolism. Both overt hypothyroidism and hyperthyroidism result in abnormalities of lipid profile. However, changes in serum lipid profiles in patients with subclinical hypothyroidi...
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ژورنال
عنوان ژورنال: Nature Reviews Endocrinology
سال: 2018
ISSN: 1759-5029,1759-5037
DOI: 10.1038/nrendo.2018.10